Opportunity Information: Apply for PA 19 270
The PHS 2019-02 Omnibus Solicitation from the National Institutes of Health (NIH) is a parent funding opportunity announcement (FOA) that supports Small Business Technology Transfer (STTR) projects under the R41 and R42 mechanisms. It is designed to help U.S. small business concerns move promising, early-stage biomedical and behavioral innovations from research toward product development by partnering with a nonprofit research institution. In practical terms, the FOA is meant for small companies that have a viable R and D idea aligned with one or more NIH awarding components and that can benefit from a formal collaboration with an academic or other eligible research partner to advance the underlying science and the enabling technology.
This opportunity is part of NIH's broader small business innovation ecosystem and points applicants to the NIH SBIR/STTR Program Descriptions and Research Topics associated with PHS 2019-2. Those topic areas reflect NIH's wide health-related mission, so projects can span many domains, including but not limited to disease diagnostics, therapeutics, prevention technologies, health IT, medical devices, research tools, and other enabling platforms that address NIH priorities. The listing also shows that the program is categorized under multiple broad public benefit areas (such as health, education, environment, food and nutrition, and social services), reflecting how NIH-supported technologies can intersect with different facets of public health and service delivery.
A central limitation of this specific parent FOA is that clinical trials are not allowed. That means applicants must not propose a study that meets the NIH definition of a clinical trial, even if the work relates to human health. Applicants can still pursue a range of preclinical development and translational activities, such as laboratory validation, prototype development, algorithm development and testing using non-trial approaches, benchtop testing, animal studies, usability or feasibility work that does not meet the clinical trial definition, and other non-clinical trial research that strengthens the evidence base for a technology. Organizations that anticipate the need to conduct a clinical trial must look for a different NIH FOA specifically permitting clinical trials rather than using this parent announcement.
Eligibility is primarily limited to U.S. small business concerns, and the FOA is explicit about restrictions on foreign participation. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. However, the announcement notes that foreign components, as defined in the NIH Grants Policy Statement, may be allowed in certain circumstances, which typically means discrete elements of the work could potentially be performed outside the U.S. if justified and permitted under NIH policy, but the applicant organization itself must be an eligible U.S. small business and must meet the STTR requirements for partnering with an appropriate research institution.
Administratively, this is a discretionary grant program from NIH, listed under funding opportunity number PA-19-270. The original posting date in the source data is May 7, 2019, with an original closing date shown as July 6, 2020. The source data does not specify an award ceiling or the expected number of awards, which often means budgets and award volumes can vary by institute, topic area, and the quality and competitiveness of the submitted applications. The FOA is associated with many CFDA numbers, reflecting participation across multiple NIH institutes and centers and the breadth of mission areas that can be supported through this omnibus solicitation.
Overall, this FOA is best understood as an NIH-wide entry point for U.S. small businesses seeking STTR funding for non-clinical-trial research and development projects that align with NIH priorities, using the phased R41/R42 structure to support early feasibility and more advanced development work in collaboration with a research institution.Apply for PA 19 270
- The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.307, 93.350, 93.351, 93.361, 93.393, 93.394, 93.395, 93.396, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.856, 93.859, 93.865, 93.866, 93.867, 93.879.
- This funding opportunity was created on 2019-05-07.
- Applicants must submit their applications by 2020-07-06. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Frequently Asked Questions (FAQs)
What is the PHS 2019-02 Omnibus Solicitation (PA-19-270)?
PA-19-270 is an NIH parent funding opportunity announcement (FOA) under the PHS 2019-02 Omnibus Solicitation. It supports Small Business Technology Transfer (STTR) projects and is intended to help U.S. small business concerns advance early-stage biomedical and behavioral innovations from research toward product development through a formal partnership with a nonprofit research institution.
Which NIH funding mechanisms does this FOA support?
This parent FOA supports STTR projects under the R41 and R42 mechanisms, reflecting a phased structure: early feasibility work (R41) and more advanced development work (R42).
Who is this opportunity meant for?
It is meant for eligible U.S. small business concerns that have a viable research and development (R&D) idea aligned with one or more NIH awarding components and that would benefit from collaborating with an academic or other eligible nonprofit research partner to advance the underlying science and enabling technology.
What types of projects are a good fit for this NIH STTR parent announcement?
Projects that fit include promising, early-stage biomedical and behavioral innovations moving toward product development, particularly those that align with NIH priorities and can be strengthened through a structured small business and research institution collaboration.
What topic areas can be supported under this solicitation?
The solicitation points applicants to NIH SBIR/STTR Program Descriptions and Research Topics associated with PHS 2019-2. The topics reflect NIH's broad health-related mission and can span many domains, including diagnostics, therapeutics, prevention technologies, health IT, medical devices, research tools, and other enabling platforms that address NIH priorities.
Does this FOA only cover health, or can it overlap with other public benefit areas?
While NIH is health-focused, the listing is categorized under multiple broad public benefit areas (including health, education, environment, food and nutrition, and social services). This reflects how NIH-supported technologies can intersect with different facets of public health and service delivery.
Are clinical trials allowed under this parent FOA?
No. A central limitation of this specific parent FOA is that clinical trials are not allowed. Applicants must not propose a study that meets the NIH definition of a clinical trial, even if the work relates to human health.
If clinical trials are not allowed, what kinds of activities can still be supported?
Applicants can pursue a range of non-clinical-trial research and translational activities, such as laboratory validation, prototype development, algorithm development and testing using non-trial approaches, benchtop testing, animal studies, and usability or feasibility work that does not meet the NIH clinical trial definition, as well as other non-clinical-trial research that strengthens the evidence base for a technology.
What should an applicant do if their project will need a clinical trial?
If a clinical trial is anticipated, applicants should look for a different NIH FOA that specifically permits clinical trials, rather than using this parent announcement.
What organizations are eligible to apply?
Eligibility is primarily limited to U.S. small business concerns. The applicant organization must be an eligible U.S. small business and must meet the STTR requirements for partnering with an appropriate research institution.
Is a research institution partner required?
Yes. This is an STTR-focused opportunity designed around a formal collaboration between a U.S. small business and a nonprofit research institution (or other eligible research partner) to advance the science and enabling technology.
Are foreign organizations eligible to apply?
No. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply under this FOA.
Can a U.S. organization apply if parts of it are outside the United States?
No. Non-domestic components of U.S. organizations are also not eligible to apply.
Are any foreign components allowed at all?
The announcement notes that foreign components (as defined in the NIH Grants Policy Statement) may be allowed in certain circumstances. This typically means discrete elements of the work could potentially be performed outside the U.S. if justified and permitted under NIH policy, but the applicant must still be an eligible U.S. small business and meet STTR partnering requirements.
Which federal agency runs this grant program?
The program is administered by the National Institutes of Health (NIH) and is described as a discretionary grant program.
What is the funding opportunity number for this announcement?
The funding opportunity number (FOA number) associated with this opportunity is PA-19-270.
When was this opportunity originally posted and when did it close (per the source data)?
The source data lists an original posting date of May 7, 2019, and an original closing date of July 6, 2020.
Does the source information list a maximum award amount or an expected number of awards?
No. The source data does not specify an award ceiling or the expected number of awards. This often indicates that budgets and award volumes can vary based on institute, topic area, and the competitiveness and quality of applications.
Why are there many CFDA numbers associated with this FOA?
The FOA is associated with many CFDA numbers because multiple NIH institutes and centers participate, and the solicitation covers a wide breadth of mission areas that can be supported through this omnibus announcement.
How should applicants think about the purpose of this parent FOA?
It is best understood as an NIH-wide entry point for U.S. small businesses seeking STTR funding for non-clinical-trial R&D projects aligned with NIH priorities, using the R41/R42 phased structure and a required collaboration with a research institution.
Where does this FOA fit within NIH's broader small business programs?
This opportunity is part of NIH's broader small business innovation ecosystem and points applicants to the NIH SBIR/STTR Program Descriptions and Research Topics associated with PHS 2019-2.
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| Funding Opportunity |
|---|
| Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional) Apply for PA 20 135 Funding Number: PA 20 135 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) Apply for PA 20 166 Funding Number: PA 20 166 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required) Apply for PA 20 187 Funding Number: PA 20 187 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) Apply for PA 20 185 Funding Number: PA 20 185 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed) Apply for PA 20 188 Funding Number: PA 20 188 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required) Apply for PA 20 197 Funding Number: PA 20 197 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) Apply for PA 20 207 Funding Number: PA 20 207 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required) Apply for PA 20 206 Funding Number: PA 20 206 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed) Apply for PA 20 205 Funding Number: PA 20 205 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed) Apply for PA 20 203 Funding Number: PA 20 203 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) Apply for PA 20 222 Funding Number: PA 20 222 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplement for Research on Dietary Supplements (Admin Supp-Clinical Trial Not Allowed) Apply for PA 20 227 Funding Number: PA 20 227 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $1,000,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) Apply for PA 20 242 Funding Number: PA 20 242 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) Apply for PA 20 246 Funding Number: PA 20 246 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 20 245 Funding Number: PA 20 245 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 20 248 Funding Number: PA 20 248 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity) Apply for PA 20 251 Funding Number: PA 20 251 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2020-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) Apply for PA 20 261 Funding Number: PA 20 261 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2020-2 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) Apply for PA 20 262 Funding Number: PA 20 262 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2020-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) Apply for PA 20 260 Funding Number: PA 20 260 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
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