Opportunity Information: Apply for HT9425 23 BCRP TBCCDA 2

The DoD Breast Cancer, Transformative Breast Cancer Consortium Development Award (FY23) is a planning-and-launch mechanism from the Department of Defense (administered through the U.S. Army Medical Research Acquisition Activity, USAMRAA) designed to help teams get a major, multi-institutional breast cancer research consortium ready for a future full-scale competition. The intent is not to fund a mature consortium at full operating capacity yet, but to give applicants dedicated time and support to bring the right people together, build the structure that will let the consortium function smoothly, and produce the early evidence needed to justify and strengthen a later application to the Transformative Breast Cancer Consortium Award (a separate, future funding opportunity, contingent on funds). In other words, this development award is meant to move a promising idea and a loosely connected set of collaborators into a well-organized consortium with shared plans, shared tools, and preliminary results that show the approach is feasible and integrated.

A central feature of this opportunity is building the consortium framework itself. Applicants are expected to develop the infrastructure of a multi-institutional research team that intentionally includes scientists, clinicians, and breast cancer consumer advocates. The emphasis is on forming appropriate collaborations and clearly defining how the different institutions and disciplines will integrate their work rather than operating as disconnected projects. The award supports the creation of practical management components such as research management and administrative management structures, communication plans that keep partners aligned, and an intellectual property plan to address ownership, data sharing, and downstream commercialization or implementation considerations. Alongside these organizational elements, the award also supports generating preliminary data that can serve as proof of concept and/or demonstrate how multiple project components will fit together, acquiring key research resources needed to get the consortium positioned for larger-scale work, and developing a framework for the statistical analyses that will be necessary to evaluate outcomes in a rigorous and coordinated way across the team.

Breast cancer consumer advocates are not optional or symbolic participants under this mechanism; they must be active participants in both the development and execution of the award. That requirement signals that applicants should plan for advocates to have meaningful roles in shaping priorities, ensuring patient-centered relevance, and informing how the consortium communicates, designs studies, and interprets impact. This is aligned with the consortium-development goal: the DoD is effectively asking applicants to demonstrate early that the team can operate as a cohesive, stakeholder-informed enterprise, not just a collection of labs.

Structurally, the opportunity is offered as either a cooperative agreement or a grant under the DoD breast cancer research portfolio (CFDA 12.420) within the broader category of science, technology, and research and development. Eligibility is described as unrestricted, meaning it is broadly open to many entity types, subject to any additional eligibility clarifications contained in the full announcement. For FY23, the agency anticipated making one award. The posting lists an award ceiling of 0, which typically indicates that applicants must rely on the program announcement for specific budget guidance or that the ceiling is not provided in the summary field, so the detailed announcement would be the authoritative source for allowable costs and budget limits.

This funding opportunity also sets expectations around how applicants position themselves relative to the future, full consortium award. Recipients of the development award are expected to submit an application to compete for the full Transformative Breast Cancer Consortium Award in a future fiscal year (if offered and funded). At the same time, the DoD makes clear that receiving a development award is not a prerequisite for applying to the full award later, so teams can pursue the full consortium mechanism without having held this planning award. There is also a key restriction for FY23 leadership roles: an investigator may be named as the Consortium Director on an application to either the development award or the full consortium award mechanism, but not both in the same cycle. Details about the full Transformative Breast Cancer Consortium Award are provided under a separate program announcement (HT9425-23-BCRP-TBCCA-2), reinforcing that this development award is its own distinct pathway focused on readiness, integration, and early validation rather than full execution at scale.

Administrative details from the source summary include the opportunity number HT9425-23-BCRP-TBCCDA-2, a creation date of May 2, 2023, and an original closing date of August 8, 2023, indicating it was a time-limited FY23 competition. Overall, the opportunity is best understood as seed and scaffolding support for a large, transformative consortium effort: it funds the hard early work of building a functional multi-institution partnership with advocates at the table, aligning governance and communication, assembling resources, and producing preliminary evidence and analysis plans that make a future full consortium application credible and competitive.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Breast Cancer, Transformative Breast Cancer Consortium Development Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on May 02, 2023.
  • Applicants must submit their applications by Aug 08, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for HT9425 23 BCRP TBCCDA 2

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FAQs: DoD Breast Cancer, Transformative Breast Cancer Consortium Development Award (FY23)

What is the Transformative Breast Cancer Consortium Development Award (FY23)?

It is a Department of Defense (DoD) planning-and-launch funding mechanism intended to help teams prepare a major, multi-institutional breast cancer research consortium for a future full-scale competition. It supports the early work required to turn a promising concept and a loosely connected group of collaborators into a well-organized, integrated consortium.

Which agency administers this opportunity?

The opportunity is administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the DoD breast cancer research portfolio.

What is the main purpose of this award?

The main purpose is to build and launch the consortium framework itself: bringing the right people together across institutions, establishing governance and management structures, creating communication and coordination plans, addressing intellectual property considerations, and generating early evidence (preliminary data) to strengthen a later application to the full Transformative Breast Cancer Consortium Award (if offered and funded in a future fiscal year).

Is this award intended to fund a fully operational, mature consortium?

No. The intent is explicitly not to fund a mature consortium operating at full capacity. This mechanism is meant to fund readiness, integration, and early validation activities that position the team for a future full-scale consortium competition.

What types of activities and deliverables does this award support?

Based on the opportunity description, supported activities include:

  • Building multi-institutional consortium infrastructure and team integration across disciplines and sites
  • Developing research management and administrative management structures
  • Creating communication plans to keep partners aligned
  • Developing an intellectual property plan (addressing ownership, data sharing, and downstream commercialization or implementation considerations)
  • Generating preliminary data as proof of concept and/or to demonstrate how project components fit together
  • Acquiring key research resources needed to position the consortium for larger-scale work
  • Developing a framework for statistical analyses needed to evaluate outcomes rigorously and consistently across the team

What is meant by a "multi-institutional" consortium in this context?

The opportunity emphasizes a research team spanning multiple institutions and disciplines that integrates work intentionally. The goal is not a set of disconnected projects, but a coordinated consortium with shared plans, shared tools, and a structure that supports smooth functioning across partners.

Who should be included in the consortium team?

The team is expected to include scientists, clinicians, and breast cancer consumer advocates. The program places clear emphasis on intentionally forming appropriate collaborations and defining how different institutions and disciplines will integrate their efforts.

Are breast cancer consumer advocates required?

Yes. Breast cancer consumer advocates must be active participants in both the development and execution of the award. They are described as not optional or symbolic, meaning applicants should plan for meaningful roles in shaping priorities, ensuring patient-centered relevance, and informing communication, study design, and interpretation of impact.

What does "active participation" by consumer advocates imply for applicants?

The description indicates advocates should have substantive involvement in the consortium's work, including helping shape priorities, ensuring relevance to patients, and informing how the consortium communicates, designs studies, and interprets impact. The expectation is that the team demonstrates it can function as a cohesive, stakeholder-informed enterprise early in the process.

What funding instrument(s) may be used for this opportunity?

The opportunity may be offered as either a cooperative agreement or a grant.

What is the CFDA number associated with this opportunity?

The CFDA number listed is 12.420.

What is the opportunity number for this FY23 announcement?

The opportunity number is HT9425-23-BCRP-TBCCDA-2.

When was this opportunity created and when did it close?

The posting lists a creation date of May 2, 2023, and an original closing date of August 8, 2023, indicating it was a time-limited FY23 competition.

How many awards did the agency anticipate making for FY23?

For FY23, the agency anticipated making one award.

What is the award ceiling?

The summary lists an award ceiling of 0. This typically signals that applicants should rely on the full program announcement for the authoritative budget guidance, including allowable costs and any budget limits, rather than the summary field.

What does "eligibility is unrestricted" mean here?

Eligibility is described as unrestricted, meaning it is broadly open to many entity types, subject to any additional eligibility clarifications in the full announcement.

How does this Development Award relate to the future Transformative Breast Cancer Consortium Award?

This Development Award is designed to prepare teams for a future application to the full Transformative Breast Cancer Consortium Award (a separate funding opportunity, contingent on funds). It focuses on planning, consortium formation, infrastructure, integration, and preliminary evidence that can make a later full application stronger and more credible.

Are recipients expected to apply for the future full Transformative Breast Cancer Consortium Award?

Yes. Recipients of the Development Award are expected to submit an application to compete for the full Transformative Breast Cancer Consortium Award in a future fiscal year, if that opportunity is offered and funded.

Is receiving this Development Award required in order to apply for the future full award?

No. The DoD makes clear that receiving a Development Award is not a prerequisite for applying to the full Transformative Breast Cancer Consortium Award later.

Is there a leadership restriction related to the Consortium Director role for FY23?

Yes. For FY23, an investigator may be named as the Consortium Director on an application to either the Development Award or the full consortium award mechanism, but not both in the same cycle.

Where are the details for the full Transformative Breast Cancer Consortium Award provided?

The full Transformative Breast Cancer Consortium Award is described under a separate program announcement: HT9425-23-BCRP-TBCCA-2.

What kind of evidence is this Development Award meant to help generate?

The award supports generating preliminary data that can function as proof of concept and/or demonstrate how multiple consortium components fit together in an integrated way. It also supports creating the statistical analysis framework needed for coordinated, rigorous outcome evaluation across the team.

Does this award emphasize integration across projects and institutions?

Yes. A major emphasis is on clearly defining how institutions and disciplines will integrate their work, rather than operating as disconnected projects. The award supports structures and plans that help the consortium function smoothly as a coordinated enterprise.

What management and planning components are specifically called out?

The opportunity specifically highlights developing research management and administrative management structures, communication plans, and an intellectual property plan addressing ownership, data sharing, and downstream commercialization or implementation considerations.

What broad category does this opportunity fall under?

The summary places it within science, technology, and research and development.

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