Opportunity Information: Apply for RFA AG 26 007
The National Institute on Aging (NIA), part of the National Institutes of Health (NIH), is soliciting applications for a Cooperative Agreement (U24) to run the Artificial Intelligence and Technology Collaboratory Coordinating Center (AITCC) under the broader NIA Artificial Intelligence and Technology Collaboratory (AITC) Program. This opportunity is designed to strengthen aging research and Alzheimer’s disease and related dementias (AD/ADRD) research by accelerating the development, evaluation, and real-world implementation of artificial intelligence methods and technology-enabled approaches. The award mechanism is a U24 cooperative agreement, which typically means the NIH expects substantial programmatic involvement from NIA staff compared to a standard grant, with the Coordinating Center working closely with NIH and the broader AITC network. Clinical trials are not allowed under this specific funding announcement.
At its core, the AITCC is meant to function as the connective tissue for the entire AITC Program. The NOFO describes three central responsibilities. First, the Coordinating Center will serve as the program hub, facilitating and coordinating activities across the AITC portfolio. In practice, that usually means establishing consistent processes for communication, aligning timelines and shared milestones across projects, convening meetings and working groups, supporting cross-project collaboration, and helping different research teams learn from one another rather than operating in silos. Second, the AITCC will centralize and lead stakeholder engagement for the program. Stakeholders in this space commonly include older adults and care partners, clinicians, health systems, long-term care and community-based service providers, payers, technology developers, ethicists, and policy leaders. The expectation is that the Coordinating Center will create structured, ongoing ways to bring these voices into the program so that AITC-supported tools and methods are useful, usable, equitable, and implementable in real-world aging and dementia contexts. Third, the AITCC is expected to broaden the program’s national reach and scientific impact by actively disseminating information about AITC and recruiting new researchers to participate in program activities and use program resources. This dissemination role often includes maintaining a strong public-facing presence (for example, a program website and communications channels), producing toolkits or guidance materials, sharing findings and best practices, hosting webinars or training events, and building on-ramps for investigators who are new to aging, AD/ADRD, implementation science, or responsible AI in health.
The opportunity (Funding Opportunity Number RFA-AG-26-007) falls under the health funding activity category and is associated with CFDA 93.866. It is labeled as a discretionary funding opportunity using the cooperative agreement instrument. The announcement lists an original application due date of 2025-10-15 and a creation date of 2025-09-10. While an award ceiling and expected number of awards are not specified in the provided text, applicants should assume the budget and scope will need to credibly support national-scale coordinating functions, including personnel for program management, stakeholder engagement, communications, and coordination infrastructure.
Eligibility is broad across U.S.-based organizations. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled and private institutions of higher education; federally recognized Native American tribal governments; public housing authorities/Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses. The NOFO also explicitly highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. At the same time, the announcement is clear about restrictions on foreign involvement: non-U.S. entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed.
Overall, this NOFO is less about proposing a single stand-alone research project and more about proposing a credible, well-governed national coordinating center that can unify a multi-project program focused on AI and technology for aging and AD/ADRD. The strongest applications are likely to be those that demonstrate practical experience coordinating complex, multi-stakeholder research networks; a thoughtful plan for stakeholder engagement that is continuous rather than one-off; and an active dissemination and recruitment strategy that brings new investigators into the field while making AITC resources accessible and widely used.Apply for RFA AG 26 007
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Artificial Intelligence and Technology Collaboratory Coordinating Center (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
- This funding opportunity was created on 2025-09-10.
- Applicants must submit their applications by 2025-10-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: NIA/NIH Artificial Intelligence and Technology Collaboratory Coordinating Center (AITCC) - U24 (RFA-AG-26-007)
What is this funding opportunity?
This is a National Institute on Aging (NIA), National Institutes of Health (NIH) funding opportunity to support a Cooperative Agreement (U24) to operate the Artificial Intelligence and Technology Collaboratory Coordinating Center (AITCC) under the broader NIA Artificial Intelligence and Technology Collaboratory (AITC) Program.
What is the purpose of the AITCC?
The AITCC is intended to serve as the coordinating hub, or connective tissue, for the entire AITC Program. Its role is to help unify and accelerate program-wide efforts that strengthen aging research and Alzheimer’s disease and related dementias (AD/ADRD) research by advancing AI methods and technology-enabled approaches and supporting their evaluation and real-world implementation.
What does the AITC Program aim to advance?
The AITC Program is designed to accelerate the development, evaluation, and real-world implementation of artificial intelligence methods and technology-enabled approaches that support aging research and AD/ADRD research.
What is the award mechanism for this opportunity?
The award mechanism is a U24 cooperative agreement.
What does a U24 cooperative agreement imply for how the project will be run?
A U24 cooperative agreement generally indicates substantial programmatic involvement by NIH staff (here, NIA staff) compared to a typical grant. Under this model, the Coordinating Center is expected to work closely with NIH and the broader AITC network rather than operating fully independently.
Are clinical trials allowed under this funding announcement?
No. Clinical trials are not allowed under this specific funding announcement.
What are the main responsibilities of the AITCC described in the NOFO?
The NOFO describes three central responsibilities: (1) serving as the program hub to coordinate activities across the AITC portfolio, (2) centralizing and leading stakeholder engagement for the program, and (3) broadening national reach and scientific impact through dissemination and recruitment of researchers to participate in AITC activities and use AITC resources.
What does it mean to serve as the program hub for AITC?
Serving as the program hub typically includes establishing consistent processes for communication, aligning timelines and shared milestones across projects, convening meetings and working groups, supporting cross-project collaboration, and enabling teams to learn from one another rather than operating in silos.
What is expected for stakeholder engagement?
The Coordinating Center is expected to centralize and lead stakeholder engagement by creating structured, ongoing ways for stakeholders to inform the program so that AITC-supported tools and methods are useful, usable, equitable, and implementable in real-world aging and dementia contexts.
Who are considered stakeholders for this program?
Stakeholders commonly include older adults and care partners, clinicians, health systems, long-term care and community-based service providers, payers, technology developers, ethicists, and policy leaders.
What does the dissemination and recruitment role include?
This role includes actively disseminating information about AITC and recruiting new researchers to participate in program activities and use program resources. It often involves maintaining a public-facing presence such as a program website and communications channels, producing toolkits or guidance materials, sharing findings and best practices, hosting webinars or training events, and building clear on-ramps for investigators new to aging, AD/ADRD, implementation science, or responsible AI in health.
Is this opportunity mainly for a stand-alone research project?
No. The NOFO is described as being less about proposing a single stand-alone research project and more about proposing a credible, well-governed national coordinating center that can unify a multi-project program focused on AI and technology for aging and AD/ADRD.
Which NIH Institute is sponsoring this opportunity?
The sponsoring Institute is the National Institute on Aging (NIA), which is part of the National Institutes of Health (NIH).
What is the Funding Opportunity Number?
The Funding Opportunity Number is RFA-AG-26-007.
What is the CFDA number associated with this opportunity?
The opportunity is associated with CFDA 93.866.
What is the funding activity category?
The opportunity falls under the health funding activity category.
When is the application due?
The announcement lists an original application due date of 2025-10-15.
When was this opportunity created?
The announcement lists a creation date of 2025-09-10.
Is there an award ceiling listed?
No award ceiling is specified in the provided information.
Is the expected number of awards listed?
No expected number of awards is specified in the provided information.
What should applicants assume about the scale of the budget and scope?
Based on the described responsibilities, applicants should assume the budget and scope will need to credibly support national-scale coordinating functions, including personnel for program management, stakeholder engagement, communications, and coordination infrastructure.
Who is eligible to apply?
Eligibility is broad across U.S.-based organizations. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled and private institutions of higher education; federally recognized Native American tribal governments; public housing authorities/Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses.
Are specific institution and organization types explicitly highlighted as eligible?
Yes. The NOFO explicitly highlights additional eligible applicant types including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.
Are non-U.S. (foreign) organizations eligible to apply?
No. Non-U.S. entities are not eligible to apply.
Can a U.S. organization include a non-U.S. component in the application?
No. Non-U.S. components of U.S. organizations are not eligible.
Are foreign components allowed in any form?
No. Foreign components (as defined by NIH policy) are not allowed.
What kinds of capabilities are likely important for a competitive application?
Based on the description provided, strong applications are likely to demonstrate practical experience coordinating complex, multi-stakeholder research networks; a stakeholder engagement plan that is continuous rather than one-off; and an active dissemination and recruitment strategy that brings new investigators into the field while making AITC resources accessible and widely used.
What kinds of staffing or functional areas are implied by the coordinating center responsibilities?
The described national coordinating functions imply staffing and capacity for program management, stakeholder engagement, communications and public-facing dissemination, and the infrastructure needed to coordinate activities across a multi-project portfolio.
How does this coordinating center relate to the broader AITC network?
The AITCC is expected to work closely with NIH and the broader AITC network to coordinate activities, align milestones, convene groups, support collaboration across projects, and increase the program's national reach and impact through dissemination and recruitment.
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